Research Article of the Month!
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A Case Report of Cryoneurolysis With Factor VIII Administration for Cerebral Palsy-related Spasticity in a Patient With Hemophilia A
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Summary of the article:
This case study explores cryoneurolysis as a potential alternative treatment for muscle stiffness (spasticity) in people with cerebral palsy, particularly those with hemophilia A, who are at higher risk of bleeding with traditional treatments like botulinum toxin (BoNT) injections. The study focuses on a 14-year-old boy with cerebral palsy and hemophilia A who underwent cryoneurolysis after receiving a clotting protein infusion (Factor VIII) to minimize bleeding risk. The procedure, which uses extreme cold to temporarily block nerve signals and reduce muscle stiffness, was successful, with immediate improvements in range of motion and functional use of his arm. These benefits lasted for at least eight months, surpassing the typical effectiveness period of BoNT injections. The study concludes that cryoneurolysis is a safe and promising option for spasticity management, especially for those with bleeding disorders, though further research is needed to confirm its long-term safety and effectiveness
